The Science of Clinical Renewal
AT HOME
Decoding the 1450nm Non-Ablative Fractional Laser Technology behind the Iris.
Why Skin Ages: The Role of Collagen
Collagen accounts for approximately 70–80% of the dermal matrix and serves as the structural framework responsible for skin firmness, elasticity, and resilience.
Beginning in the mid-20s, collagen production gradually declines while existing collagen fibers become fragmented and disorganized. This process contributes to enlarged pores, uneven texture, acne scarring, fine lines, wrinkles, and loss of skin firmness.
Effective skin rejuvenation therefore requires stimulating biological collagen remodeling—not simply improving surface hydration or temporarily tightening the skin.
The Science Behind Iris
A Wavelength Trusted by Professional Laser Systems
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1450nm is one of the most extensively studied wavelengths for non-ablative dermal remodeling and is widely used in professional dermatology and aesthetic laser platforms.
Unlike wavelengths that primarily target melanin or hemoglobin, 1450nm exhibits strong absorption by water molecules, the dominant chromophore within skin tissue.
This allows laser energy to penetrate approximately 300–500 μm into the dermis, where collagen synthesis and fibroblast activity occur.
By generating controlled thermal stimulation at this depth, 1450nm supports collagen regeneration while minimizing disruption to the epidermis. -
Water absorption at 1450nm is significantly higher than many commonly used aesthetic wavelengths, enabling efficient thermal generation precisely within the collagen-rich dermis.
Traditional bulk-heating technologies distribute energy across large treatment areas, exposing both target and non-target tissue to thermal stimulation.
Fractional laser technology takes a fundamentally different approach. Instead of treating the entire skin surface simultaneously, laser energy is divided into thousands of microscopic treatment zones (MTZs). Each microthermal zone creates a highly localized thermal stimulus while surrounding tissue remains intact.
These untreated zones serve as reservoirs of healthy cells that accelerate tissue repair and collagen remodeling. This approach enables effective dermal stimulation with minimal downtime and improved treatment comfort.
Iris utilizes proprietary Nano-Matrix™ technology to divide laser energy into ultra-fine fractional micro-beams measuring approximately 100 μm in diameter—roughly one-sixth the width of a human hair.
Each micro-beam creates a precise thermal treatment zone within the dermis while preserving adjacent tissue integrity.
This micron-level precision enables controlled collagen stimulation across the treatment area while maintaining a favorable safety and recovery profile for at-home use.
100 μm Micro-Beams • Up to 12 mJ per Micro-Beam • 2.11 J/cm² Energy Density
Most conventional fractional laser systems utilize a stamp-based delivery method, applying energy in fixed patterns that require repeated repositioning. Treatment consistency therefore depends heavily on operator technique and overlap accuracy.
Dynamic Scan™ technology replaces fixed stamping with a magnetically suspended scanning arm capable of millisecond-level control. During treatment, the system continuously performs movement, positioning, and laser delivery in a synchronized sequence, distributing more than 10,000 micro-beams within a single session. This dynamic delivery architecture enables more uniform coverage and energy distribution across the face.
What Happens Beneath Your Skin
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Weeks 1–4Fibroblast Activation
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Weeks 4-8Active Collagen Remodeling
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Week 8+Visible Improvements in Skin Quality
The biological response to 1450nm fractional laser treatment occurs in stages.
Immediately after treatment, controlled thermal stimulation activates the skin's wound-healing response. Fibroblasts become more active, initiating the synthesis of new collagen and elastin fibers.
Over subsequent weeks, collagen density increases and collagen fibers reorganize into a more structured network, contributing to improvements in texture, elasticity, wrinkles, pores, and acne-related skin concerns.
Immediately: Controlled Dermal Heating → Weeks 1–4: Fibroblast Activation → Weeks 4–8: Active Collagen Remodeling → Week 8+: Visible Improvements in Skin Quality
Safety
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Baseline(Pre-Treatment)
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Post-Treatment(Week 8)
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Follow-Up AfterRest Period (Week 12)
A third-party human efficacy study evaluated the safety and performance of Iris over an 8-week treatment period. Results demonstrated measurable improvements in collagen regeneration, skin texture, pores, firmness, and acne-related concerns, with benefits maintained during the post-treatment observation period.
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Baseline(Pre-Treatment)
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Post-Treatment(Week 8)
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Follow-Up AfterRest Period (Week 12)
Safety by Design
Iris is engineered around a non-ablative fractional approach that stimulates dermal remodeling without disrupting the skin barrier. Combined with intelligent treatment zoning, controlled energy delivery, and Dynamic Scan™ technology, the system is designed to provide effective collagen stimulation while maintaining user comfort and minimizing downtime.
The Ultimate Age-Defying Duo
The Routine: For full-face use of both devices, we recommend separating treatments by 48 hours. When targeting different facial areas, such as Iris on the upper face and Vera on the lower face, just follow the normal usage schedule for each device.